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Factor B-IN-5

CFB Inhibitor

Factor B-IN-5 is an orally active inhibitor of complement factor B (CFB), targeting the complement system to mitigate its overactivation. This compound demonstrates significant therapeutic potential by reducing kidney damage associated with diabetic nephropathy through the enhancement of mitochondrial function and the reduction of renal tubulointerstitial inflammation and fibrosis. Factor B-IN-5 serves as a valuable reagent for research focused on the pathophysiology and treatment of diabetic nephropathy.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	1644670-23-4
Applications	CFB Inhibitor
Formula	C₂₄H₂₈N₂O₃
Molecular Weight	392.49
SMILES	CC1=CC(OC)=C(CN2CC[C@@H](C)C[C@H]2C3=CC=C(C(O)=O)C=C3)C4=C1NC=C4

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.