Fig. 1 · Structure
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Factor XI-IN-1
Factor XI Activation Inhibitor
Factor XI-IN-1 is a selective inhibitor of Factor XI activation, demonstrating an effective EC50 of 25.14 nM. This compound disrupts the intrinsic pathway of coagulation, making it a valuable tool in the study of thrombotic diseases and anticoagulant research. Its potency and mechanism of action provide significant potential for exploring therapeutic applications in clotting disorders.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2720619-72-5 |
| Applications | Factor XI Activation Inhibitor |
| Formula | C30H38N4O2 |
| Molecular Weight | 486.65 |
| SMILES | N#CC1(C2=CC=CC=C2)CCN(C(C3=NC(C)=C(C)C(C(N4CCC(C(C)(C)C)CC4)=O)=C3)=O)CC1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.