Fig. 1 · Structure

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FAK-IN-18

FAK Inhibitor

FAK-IN-18 is a potent inhibitor of focal adhesion kinase (FAK), demonstrating an IC50 of 0.84 nM. This compound is valuable for research focused on gastric cancer, as it plays a critical role in cell adhesion, migration, and metastatic processes. FAK-IN-18 is suitable for studies investigating the regulatory mechanisms of FAK in tumor progression and provides a tool for evaluating therapeutic strategies targeting FAK signaling pathways.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 2941086-18-4
Applications FAK Inhibitor
Formula C33H34ClN7O2
Molecular Weight 596.12
SMILES
O=C(N1CCCC(C1)C2=CC(NCC3=CC=C(NC4=NC=C(C(NC5=C(C(NC)=O)C=CC=C5)=N4)Cl)C=C3)=CC=C2)C=C

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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