Fig. 1 · Structure
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FANCM-BTR PPI-IN-1
FANCM/BTR Inhibitor
FANCM-BTR PPI-IN-1 is a selective inhibitor of the FANCM/BTR protein-protein interaction, effectively preventing the localization of FANCM to telomeres. This compound demonstrates significant anticancer activity, particularly in osteosarcoma models, making it a valuable tool for studying telomere dynamics and the role of FANCM in cancer biology. Its application in research may provide insights into therapeutic strategies targeting telomere-related pathways.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 3033990-61-0 |
| Applications | FANCM/BTR Inhibitor |
| Formula | C27H35N5O2S |
| Molecular Weight | 493.66 |
| SMILES | O=S(C1=CC=C(NCC2=CN=CN2)C=C1)(N(C3CCCC3)CC4=CC=C5C(CCCN5CC)=C4)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.