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FASN-IN-7

Fatty Acid Synthase (FASN) Inhibitor

FASN-IN-7 is a potent inhibitor of human Fatty Acid Synthase (FASN), with IC50 values of 28 nM for full-length FASN and 54 nM for the FASN KR domain. This compound effectively inhibits the proliferation of various cancer cell types and alters lipid metabolism by increasing malonyl-CoA levels while reducing palmitate levels in tumor tissues. FASN-IN-7 serves as a valuable tool for researching metabolic pathways in cancer biology and the potential therapeutic modulation of FASN activity.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	1579514-16-1
Applications	Fatty Acid Synthase (FASN) Inhibitor
Formula	C₃₀H₃₁N₅O₂
Molecular Weight	493.60
SMILES	O=C1N(C[C@H]2CN(C(C3CC3)=O)CC2)C(C4=CC=C(C5=CC=C(C6=CN(C)N=C6)C=C5)C=C4)=NC71CC7

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.