Fig. 1 · Structure
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FAUC 213
Dopamine D4 Receptor Antagonist
FAUC 213 is a potent antagonist of the dopamine D4 receptor, exhibiting a binding affinity (Ki) of 2.2 nM for the human D4.4 receptor. This compound demonstrates significantly lower activity towards D2 and D3 receptors, with Kis of 3.4 μM and 5.3 μM, respectively. FAUC 213 is capable of crossing the blood-brain barrier, suggesting its utility in the study of neurological conditions. Its distinct pharmacological profile supports research into atypical antipsychotic therapies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 337972-47-1 |
| Applications | Dopamine D4 Receptor Antagonist |
| Formula | C18H19ClN4 |
| Molecular Weight | 326.82 |
| SMILES | ClC(C=C1)=CC=C1N(CC2)CCN2CC3=NN4C=CC=CC4=C3 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.