FBnG-(Cys-acetamide)-CH2-PEG3-CH2-CH2-CH2-NH2 is a tag-linker conjugate of AUTAC designed to facilitate targeted protein degradation. This compound integrates a p-fluorobenzylguanine (FBnG) tag with a glycol spacer, enabling effective K63-linked polyubiquitination. It demonstrates significant biological activity by promoting the degradation of mitochondrial proteins in HeLa cells, making it a valuable tool for researchers studying mitochondrial dynamics and protein homeostasis.
FBnG-(Cys-acetamide)-CH2-PEG3-CH2-CH2-CH2-NH2 is a tag-linker conjugate of AUTAC designed to facilitate targeted protein degradation. This compound integrates a p-fluorobenzylguanine (FBnG) tag with a glycol spacer, enabling effective K63-linked polyubiquitination. It demonstrates significant biological activity by promoting the degradation of mitochondrial proteins in HeLa cells, making it a valuable tool for researchers studying mitochondrial dynamics and protein homeostasis.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
