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FcⅢ-GN3

IgG degrader

FcⅢ-GN3 is a dual-functional peptide targeting IgG degradation through enhanced internalization mechanisms in HepG2 cells. Upon internalization, IgG localizes within late endosomes and lysosomes, promoting clearance via the liver's natural pathway. This agent is particularly valuable for investigating diseases associated with elevated IgG levels, facilitating the exploration of therapeutic interventions in related pathologies.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Degrader
CAS Number	2378837-81-9
Applications	IgG degrader
Formula	C₁₄₀H₂₁₉N₂₉O₅₄S₂
Molecular Weight	3236.53

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.