Fig. 1 · Structure

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FD-895

Spliceosome Modulator

FD-895 is a spliceosome modulator that selectively targets the SF3b subunit, influencing RNA splicing mechanisms such as intron retention and alternative splicing. This compound exhibits significant biological activity by inducing apoptosis in cancer cells. FD-895 is particularly relevant in cancer research, with applications in studying chronic lymphocytic leukemia (CLL) and other malignancies.

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Specifications

Manufacturer Adooq Bioscience
Actions Modulator
CAS Number 147025-57-8
Applications Spliceosome Modulator
Formula C31H50O9
Molecular Weight 566.72
SMILES
CC[C@H](OC)[C@H]([C@]1([H])[C@]([C@H](O)[C@H](C)/C=C/C=C([C@@H](O2)[C@H](/C=C/[C@@H]([C@](O)(CC[C@@H](O)CC2=O)C)OC(C)=O)C)\C)([H])O1)C

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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