Fig. 1 · Structure
Documents & Downloads
FD44
NCS-1-Ric8a Inhibitor
FD44 is a phenothiazine small molecule that functions as an inhibitor of the interaction between neuronal calcium sensor 1 (NCS-1) and the guanine exchange factor Ric8a. This interaction is crucial for regulating synapse number and neurotransmitter release probability. In studies utilizing a Drosophila model of fragile X syndrome (FXS), FD44 demonstrated the ability to restore normal synapse numbers and improve associative learning, making it a valuable reagent for research into synaptic function and neurodevelopmental disorders.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 68207-21-6 |
| Applications | NCS-1-Ric8a Inhibitor |
| Formula | C19H21N3OS |
| Molecular Weight | 339.45 |
| SMILES | O=C(CN1CCCCC1)NN2C3=C(SC4=C2C=CC=C4)C=CC=C3 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.