Federelin

Catalog No.: A60704
GnRH analogue
Federelin is a gonadotropin-releasing hormone (GnRH) analog that acts by binding to GnRH receptors to stimulate the secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH). This compound plays a significant role in reproductive biology and is used in research applications involving hormonal regulation, fertility studies, and endocrine system investigations. Its ability to modulate hormone levels makes it a valuable tool in studying reproductive health and related disorders.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionFederelin is a gonadotropin-releasing hormone (GnRH) analog that acts by binding to GnRH receptors to stimulate the secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH). This compound plays a significant role in reproductive biology and is used in research applications involving hormonal regulation, fertility studies, and endocrine system investigations. Its ability to modulate hormone levels makes it a valuable tool in studying reproductive health and related disorders.
Product Information
Catalog NumA60704
FormulaC62H81N17O13
Molecular Weight1272.41
CAS Number57521-78-5
Sequence{pGlu}-His-Trp-Ser-Tyr-{dPhe}-Leu-Arg-Pro-Gly
Sequence shortening{pGlu}-HWSY-{dPhe}-LRPG
SMILESC([C@H](NC([C@H](CC1=CN=CN1)NC(=O)[C@H]2NC(=O)CC2)=O)C(N[C@H](C(N[C@@H](CC3=CC=C(O)C=C3)C(N[C@H](CC4=CC=CC=C4)C(N[C@H](C(N[C@H](C(=O)N5[C@H](C(NCC(N)=O)=O)CCC5)CCCNC(=N)N)=O)CC(C)C)=O)=O)=O)CO)=O)C=6C=7C(NC6)=CC=CC7
SynonymsGonadorelin[6-D-Phe]; [D-Phe6]GnRH
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