Fig. 1 · Structure
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Felodipine-d3
Stable Isotope
Felodipine-d3 is a deuterated form of Felodipine, a potent vasoselective calcium channel antagonist. It effectively lowers blood pressure by selectively targeting vascular smooth muscle, particularly in resistance vessels. In addition to its antihypertensive properties, Felodipine has been shown to induce autophagy and can penetrate the blood-brain barrier, making it useful for various biological studies and drug development research applications. This stable isotope is ideal for pharmacokinetic and metabolic studies involving Felodipine.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1219795-30-8 |
| Applications | Stable Isotope |
| Formula | C18H16D3Cl2NO4 |
| Molecular Weight | 387.27 |
| SMILES | CCOC(C1=C(C)NC(C)=C(C(OC)=O)C1C2=C(C(Cl)=C([2H])C([2H])=C2[2H])Cl)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.