Fig. 1 · Structure
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Felotaxel
Drug Derivative
Felotaxel is a derivative of Docetaxel, primarily targeting microtubules to inhibit cancer cell proliferation. It exhibits significant antitumor activity and demonstrates distinct pharmacokinetic properties in preclinical models, particularly in rats. The compound is rapidly distributed within normal tissues, with renal excretion serving as the primary elimination pathway, and its plasma protein binding capacity shows a nearly linear relationship with concentration. Felotaxel's unique profile makes it a valuable reagent for cancer research and therapeutic studies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 944154-59-0 |
| Applications | Drug Derivative |
| Formula | C50H64N2O15 |
| Molecular Weight | 933.05 |
| Synonyms | SHR110008 |
| SMILES | CC(O[C@@]1([C@](C[C@@H]2O)([H])OC1)[C@]([C@@H]([C@@](C(C)3C)(C[C@@H]4OC([C@H](O)[C@H](C5=CC=CC=C5)NC(OC(C)(C)C)=O)=O)O)OC(C6=CC=CC=C6)=O)([H])[C@@]2([C@@](OC7CN8[C@H](CO9)C[C@H]9C8)([H])[C@@](O7)([H])C3=C4C)C)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.