Fig. 1 · Structure
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Fenclonine hydrochloride
Trp Hydroxylase Inhibitor
Fenclonine hydrochloride is a selective and irreversible inhibitor of tryptophan hydroxylase, the rate-limiting enzyme in serotonin biosynthesis. This compound plays a critical role in research related to carcinoid syndrome by modulating serotonin levels, thus offering insights into its pathophysiology and potential therapeutic approaches. Fenclonine hydrochloride is valuable for studying serotonin-related disorders and the mechanisms of tryptophan metabolism.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 23633-07-0 |
| Applications | Trp Hydroxylase Inhibitor |
| Formula | C9H11Cl2NO2 |
| Molecular Weight | 236.10 |
| Synonyms | 4-Chloro-DL-phenylalanine hydrochloride; PCPA hydrochloride; CP-10188 hydrochloride |
| SMILES | O=C(C(CC1=CC=C(C=C1)Cl)N)O.Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.