Fig. 1 · Structure
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Fenofibrate-d6
Stable Isotope
Fenofibrate-d6 is a deuterium-labeled version of Fenofibrate, a selective agonist of the peroxisome proliferator-activated receptor alpha (PPARα) with an EC50 value of 30 μM. This compound is also known to inhibit several human cytochrome P450 isoforms, exhibiting IC50 values of 0.2 μM for CYP2C19, 0.7 μM for CYP2B6, 9.7 μM for CYP2C9, 4.8 μM for CYP2C8, and 142.1 μM for CYP3A4. Fenofibrate-d6 is valuable for pharmacokinetic studies and metabolic research involving lipid modulation and drug metabolism.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1092484-56-4 |
| Applications | Stable Isotope |
| Formula | C20H15D6ClO4 |
| Molecular Weight | 366.87 |
| SMILES | ClC1=CC=C(C=C1)C(C2=CC=C(C=C2)OC(C(OC(C)C)=O)(C([2H])([2H])[2H])C([2H])([2H])[2H])=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.