Fig. 1 · Structure
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Fenoldopam hydrochloride
D1 Receptor Agonist
Fenoldopam hydrochloride is a potent D1 receptor agonist that also functions as a lysine-specific demethylase 1 (LSD1) inhibitor, with an IC50 of 0.8974 μM. This compound exhibits significant anti-hypertensive properties and has demonstrated efficacy in inhibiting cancer cell proliferation while inducing apoptosis. Fenoldopam hydrochloride is valuable in research applications focused on cardiovascular effects and oncology studies related to dysregulated epigenetic mechanisms.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 181217-39-0 |
| Applications | D1 Receptor Agonist |
| Formula | C16H17Cl2NO3 |
| Molecular Weight | 342.22 |
| Synonyms | SKF 82526 hydrochloride |
| SMILES | ClC1=C(CCNCC2C3=CC=C(C=C3)O)C2=CC(O)=C1O.Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.