Fig. 1 · Structure
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Fenquizone
Diuretic
Fenquizone is an orally active diuretic that primarily targets the diluting segment of the nephron cortex, functioning similarly to thiazide diuretics. This compound exhibits diuretic and natriuretic effects with a potency and duration of action that, while comparable to thiazides, is weaker than that of loop diuretics. Fenquizone effectively reduces CH₂O without influencing TCH₂O or increasing calcium and phosphate excretion, and it does not affect the loop or collecting duct. It is employed in research focused on edema and hypertension.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 20287-37-0 |
| Applications | Diuretic |
| Formula | C14H12ClN3O3S |
| Molecular Weight | 337.78 |
| Synonyms | MG-13054 |
| SMILES | O=S(C1=CC2=C(NC(C3=CC=CC=C3)NC2=O)C=C1Cl)(N)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.