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Ferrioxamine B

FoxA/FpvB Ligand

Ferrioxamine B is a bacterial desferrioxamine siderophore that specifically targets the FpvB and FoxA transporters in Pseudomonas aeruginosa. It functions as a ligand, facilitating the transport of iron into bacterial cells under iron-limiting conditions. Additionally, Ferrioxamine B competitively binds to FpvB, which inhibits the uptake of thiostrepton, making it a valuable tool in research focused on bacterial iron acquisition and antibiotic resistance mechanisms. This compound is essential for studies aimed at understanding the role of siderophores in microbial physiology and pathogenesis.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	14836-73-8
Applications	FoxA/FpvB Ligand
Formula	C₂₅H₄₅FeN₆O₈
Molecular Weight	613.51
SMILES	NCCCCCN1[O-][Fe+3]23([O]=C1CCC4=O)([O-]N(CCCCCN5)C(C)=[O]3)[O-]N(CCCCCN4)C(CCC5=O)=[O]2

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.