Fig. 1 · Structure
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Fexofenadine-d10 hydrochloride
Stable Isotope
Fexofenadine-d10 hydrochloride is a deuterium-labeled derivative of Fexofenadine hydrochloride, a potent H1 receptor antagonist. This stable isotope is primarily utilized in pharmacokinetic studies and drug metabolism research, allowing for enhanced tracking of drug distribution and action in biological systems. It plays a critical role in understanding the pharmacological properties of anti-allergic agents used in the treatment of conditions such as seasonal allergic rhinitis and chronic idiopathic urticaria.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1215821-44-5 |
| Applications | Stable Isotope |
| Formula | C32H30D10ClNO4 |
| Molecular Weight | 548.18 |
| Synonyms | MDL-16455-d10 hydrochloride; Terfenadine carboxylate-d10 hydrochloride |
| SMILES | OC(C1=C([2H])C([2H])=C([2H])C([2H])=C1[2H])(C2=C([2H])C([2H])=C([2H])C([2H])=C2[2H])C3CCN(CC3)CCCC(C4=CC=C(C=C4)C(C)(C)C(O)=O)O.Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.