FFA2 Agonist-1 is a selective agonist for the Free Fatty Acid Receptor 2 (FFA2/GPR43), exhibiting an EC50 of 81 nM. This compound effectively engages β-arrestin-2 in recruitment assays and demonstrates cAMP inhibition with EC50 values of 1.2 μM and 0.53 μM, respectively. FFA2 Agonist-1 has been shown to influence appetite regulation through peptide YY (PYY) mucosal responses, limiting fat accumulation and impacting intestinal functions and food intake. It is a valuable tool for obesity research and related metabolic studies.
FFA2 Agonist-1 is a selective agonist for the Free Fatty Acid Receptor 2 (FFA2/GPR43), exhibiting an EC50 of 81 nM. This compound effectively engages β-arrestin-2 in recruitment assays and demonstrates cAMP inhibition with EC50 values of 1.2 μM and 0.53 μM, respectively. FFA2 Agonist-1 has been shown to influence appetite regulation through peptide YY (PYY) mucosal responses, limiting fat accumulation and impacting intestinal functions and food intake. It is a valuable tool for obesity research and related metabolic studies.
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