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FHND5071 (1H)

RET Inhibitor

FHND5071 (1H) is a selective inhibitor of the RET (rearrangement during transfection) tyrosine kinase, making it a valuable tool for understanding RET-driven oncogenesis. This compound demonstrates significant biological activity against various cancers associated with RET alterations, including thyroid and lung cancers. FHND5071 (1H) is intended for research applications focused on elucidating RET signaling pathways and developing targeted therapeutic strategies.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2493156-15-1
Applications	RET Inhibitor
Formula	C₃₀H₃₃N₉O
Molecular Weight	535.64
SMILES	COC1=CC=C(C=N1)CN2C3CC2CN(C3)C4=NC=C(C=C4)C5=CC(N6CCN(CC6)C)=CN7N=CC(C#N)=C57

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.