Fig. 1 · Structure

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Fibrostatin C

Prolyl Hydroxylase Inhibitor

Fibrostatin C is a potent prolyl hydroxylase inhibitor that regulates collagen biosynthesis. This compound enhances the presence of cytoplasmic granules that are immunoreactive to collagen I and III, while also suppressing the secretion of type I collagen in Tenon’s capsule fibroblasts. Fibrostatin C is of significant value for investigating wound fibrotic responses, particularly in the context of glaucoma filtering surgery.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 91776-47-5
Applications Prolyl Hydroxylase Inhibitor
Formula C18H19NO8S
Molecular Weight 409.41
Synonyms P-23924C
SMILES
O=C([C@@H](NC(C)=O)CSCC(C(O)=C1C2=O)=C(C=C1C(C(OC)=C2)=O)OC)O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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