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Fibrostatin E

Proline Hydroxylase

Fibrostatin E is a selective inhibitor of proline hydroxylase, an enzyme critical for collagen biosynthesis and cellular processes. This compound, derived from Streptomyces catenulae, demonstrates significant biological activity by modulating hypoxia-inducible factor (HIF) stabilization and influencing tissue remodeling. Fibrostatin E is useful in research applications focused on fibrosis, wound healing, and cancer progression, making it a valuable tool for studies investigating extracellular matrix dynamics and related pathologies.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	91776-44-2
Applications	Proline Hydroxylase
Formula	C₁₈H₁₉NO₈S
Molecular Weight	409.41
SMILES	OC1=C2C(C(C=C(C2=O)CO)=O)=CC(OC)=C1CSC[C@@H](C(O)=O)NC(C)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.