FIIN-2

Catalog No.: A12357

FGFR Inhibitor

FIIN-2

FIIN-2 Chemical Structure

CAS NO. 1633044-56-0

FIIN-2 is an irreversible inhibitor of FGFR1-4 with IC50 values of 3.1, 4.3, 27, and 45 nM, respectively.

Availability: In stock

Package Price Qty
5 mg
$80.00
10 mg
$140.00
25 mg
$280.00
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Biological Activity

FIIN-2 is an irreversible inhibitor of FGFR1-4 with IC50 values of 3.1, 4.3, 27, and 45 nM, respectively.
Targets
FGFR1 FGFR2 FGFR3 FGFR4
3.09 nM4.3 nM27 nM45.3 nM
In vitro DMSO 62 mg/mL (97.67 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 15.75 mL 78.77 mL 157.55 mL
0.5 mM 3.15 mL 15.75 mL 31.51 mL
1 mM 1.58 mL 7.88 mL 15.75 mL
5 mM 0.32 mL 1.58 mL 3.15 mL

*The above data is based on the productmolecular weight 634.73. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A12357
Actions Inhibitor
CAS No. 1633044-56-0
Formula C35H38N8O4
M. Wt 634.73
Purity >98%
Synonyms FIIN2, FIIN 2
SMILES O=C1N(C2=CC(OC)=CC(OC)=C2)CC(C=NC(NC3=CC=C(N4CCN(C)CC4)C=C3)=N5)=C5N1CC6=CC=C(NC(C=C)=O)C=C6
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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