FIIN-2

Catalog No.: A12357

FGFR Inhibitor

FIIN-2

FIIN-2 Chemical Structure

CAS NO. 1633044-56-0

FIIN-2 is an irreversible inhibitor of FGFR1-4 with IC50 values of 3.1, 4.3, 27, and 45 nM, respectively.

Availability: In stock

Package Price Qty
5 mg
$80.00
10 mg
$140.00
25 mg
$280.00
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Biological Activity

FIIN-2 is an irreversible inhibitor of FGFR1-4 with IC50 values of 3.1, 4.3, 27, and 45 nM, respectively.
Targets
FGFR1 FGFR2 FGFR3 FGFR4
3.09 nM4.3 nM27 nM45.3 nM
In vitro DMSO 148 mg/mL (200.3 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 15.75 mL 78.77 mL 157.55 mL
0.5 mM 3.15 mL 15.75 mL 31.51 mL
1 mM 1.58 mL 7.88 mL 15.75 mL
5 mM 0.32 mL 1.58 mL 3.15 mL

*The above data is based on the productmolecular weight 634.73. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A12357
Actions Inhibitor
M. Wt 634.73
Formula C35H38N8O4
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1633044-56-0
Synonyms FIIN2, FIIN 2
SMILES O=C1N(C2=CC(OC)=CC(OC)=C2)CC(C=NC(NC3=CC=C(N4CCN(C)CC4)C=C3)=N5)=C5N1CC6=CC=C(NC(C=C)=O)C=C6

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