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FGFR Inhibitor

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Catalog No. A12357

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
FIIN-2 5mg A12357-5

Regular Price: $80.00

Special Price: $72.00

FIIN-2 10mg A12357-10

Regular Price: $140.00

Special Price: $126.00

FIIN-2 25mg A12357-25

Regular Price: $280.00

Special Price: $252.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

FIIN-2 is an irreversible inhibitor of FGFR1-4 with IC50 values of 3.1, 4.3, 27, and 45 nM, respectively.


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Chemical Information

Catalog Num A12357
Actions Inhibitor
M. Wt 634.73
Formula C35H38N8O4
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1633044-56-0
Synonyms FIIN2, FIIN 2

Biological Activity

FIIN-2 is an irreversible inhibitor of FGFR1-4 with IC50 values of 3.1, 4.3, 27, and 45 nM, respectively.
3.09 nM4.3 nM27 nM45.3 nM


Solubility (25°C)* In vitro DMSO 148 mg/mL (200.3 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 15.75 mL 78.77 mL 157.55mL
0.5 mM 3.15 mL 15.75 mL 31.51 mL
1 mM 1.58 mL 7.88 mL 15.75 mL
5 mM 0.32 mL 1.58 mL 3.15 mL

*The above data is based on the productmolecular weight 634.73. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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