Fig. 1 · Structure
Documents & Downloads
Filanesib hydrochloride
KSP Inhibitor
Filanesib hydrochloride is a selective noncompetitive inhibitor of kinesin spindle protein (KSP), exhibiting an IC50 of 6 nM for human KSP. This compound induces cell death through apoptosis in vitro and demonstrates significant anti-proliferative activity. Filanesib is primarily utilized in research focused on cell cycle regulation and cancer therapeutics.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1385020-40-5 |
| Applications | KSP Inhibitor |
| Formula | C20H23ClF2N4O2S |
| Molecular Weight | 456.94 |
| Synonyms | ARRY-520 hydrochloride |
| SMILES | O=C(N1[C@@](C2=CC=CC=C2)(CCCN)SC(C3=CC(F)=CC=C3F)=N1)N(OC)C.[H]Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.