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FINDY

Catalog No.: A35098
DYRK1A Inhibitor
FINDY is a selective inhibitor of DYRK1A, specifically targeting its folding intermediate. It effectively inhibits autophosphorylation at Ser97, with an IC50 of 35 μM. FINDY is valuable for research on neurological disorders. Additionally, it features an alkyne group that allows it to engage in copper-catalyzed azide-alkyne cycloaddition (CuAAc), making it a versatile tool in chemical biology applications.
FINDY 1507367-37-4 DYRK1A Inhibitor
Grouped product items
Size Price Stock Qty
25mg
$935.00
In stock
50mg
$1,625.00
In stock
100mg
$2,000.00
In stock
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionFINDY is a selective inhibitor of DYRK1A, specifically targeting its folding intermediate. It effectively inhibits autophosphorylation at Ser97, with an IC50 of 35 μM. FINDY is valuable for research on neurological disorders. Additionally, it features an alkyne group that allows it to engage in copper-catalyzed azide-alkyne cycloaddition (CuAAc), making it a versatile tool in chemical biology applications.
Product Information
Catalog NumA35098
FormulaC16H17NO2S2Si
Molecular Weight347.53
CAS Number1507367-37-4
SMILESC[Si](C)(C)C#CC1=C(C=CC(/C=C2SC(NC\2=O)=S)=C1)OC
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Cell Cycle > DYRK