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$0.00 - Bih-Cheng Chen, .et al. Protective effect of Fisetin against angiotensin II-induced apoptosis by activation of IGF-IR-PI3K-Akt signaling in H9c2 cells and spontaneous hypertension rats, Phytomedicine, 2019, Apr; 57:1-8
- Jeng LB, .et al. Fisetin mediated apoptotic cell death in parental and Oxaliplatin/irinotecan resistant colorectal cancer cells in vitro and in vivo, J Cell Physiol, 2018, Sep;233(9):7134-7142 PMID: 29574877
- Kuan-Ho Lin, .et al. Bioactive flavone fisetin attenuates hypertension associated cardiac hypertrophy in H9c2 cells and in spontaneously hypertension rats, Journal of Functional Foods, 2018, 52: 212-218
Biological Activity
Fisetin is a flavonol, a structurally distinct chemical substance that belongs to the flavonoid group of polyphenols. It can be found in many plants, where it serves as a colouring agent. Possible anti-aging, anti-inflammatory, anti-cancer, and anti-viral properties of fisetin are under active scientific investigation.
Targets
| Sirtuin | ||||
| In vitro | DMSO | 57 mg/mL (199.13 mM) | |
| Water | <1 mg/mL (<1 mM) | ||
| Ethanol | 3 mg/mL (10.48 mM) | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 34.94 mL | 174.7 mL | 349.41 mL |
| 0.5 mM | 6.99 mL | 34.94 mL | 69.88 mL |
| 1 mM | 3.49 mL | 17.47 mL | 34.94 mL |
| 5 mM | 0.7 mL | 3.49 mL | 6.99 mL |
*The above data is based on the productmolecular weight 286.2. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A10388 |
|---|---|
| M. Wt | 286.2 |
| Formula | C15H10O6 |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 528-48-3 |
| Synonyms | Fustel, Viset |
| SMILES | C1=CC(=C(C=C1C2=C(C(=O)C3=C(O2)C=C(C=C3)O)O)O)O |
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