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FK 633

GPⅡbⅡa Receptor Antagonist

FK 633 is a peptide mimetic that functions as a GPⅡbⅡa receptor antagonist, inhibiting fibrinogen binding. This compound exhibits notable anti-platelet and anti-thrombotic properties, effectively disrupting platelet aggregation induced by various agonists, including ADP, collagen, thrombin, and PAF, with IC50 values of 103, 87, 98, and 239 nM, respectively. FK 633 serves as a valuable tool for research applications focused on thrombosis and platelet function.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Antagonist
CAS Number	147865-49-4
Applications	GPⅡbⅡa Receptor Antagonist
Formula	C₂₀H₂₈N₄O₇
Molecular Weight	436.46
Synonyms	FR-144633
SMILES	CC(C)[C@@H](C(O)=O)NC([C@H](CC(O)=O)NC(CCCOC1=CC=C(C(N)=N)C=C1)=O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.