Fig. 1 · Structure
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FK-739 free base
Angiotensin II Type 1 Receptor Antagonist
FK-739 free base is an angiotensin II type 1 (AT1) receptor antagonist, primarily utilized in hypertension research. This compound inhibits the binding of angiotensin II to its receptor, leading to vasodilation and decreased blood pressure. Its application extends to studying the role of the renin-angiotensin system in cardiovascular diseases and developing therapeutics for hypertension-related conditions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 133052-30-9 |
| Applications | Angiotensin II Type 1 Receptor Antagonist |
| Formula | C24H23N7 |
| Molecular Weight | 409.49 |
| SMILES | CCCCC1=NC(C=CC=N2)=C2N1CC3=CC=C(C4=C(C5=NN=NN5)C=CC=C4)C=C3 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.