FKBP12 Ligand-Linker Conjugate 1

Catalog No.: A40918
Target Protein Ligand-Linker Conjugate
FKBP12 Ligand-Linker Conjugate 1 is designed to bind the FKBP12 protein, serving as a critical component in targeted protein degradation applications. This conjugate facilitates the synthesis of PROTAC degrader MC-25B, enabling researchers to study the modulation of protein levels within cellular systems. Its utility in chemical biology makes it a valuable tool for investigating protein interaction dynamics and therapeutic development.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionFKBP12 Ligand-Linker Conjugate 1 is designed to bind the FKBP12 protein, serving as a critical component in targeted protein degradation applications. This conjugate facilitates the synthesis of PROTAC degrader MC-25B, enabling researchers to study the modulation of protein levels within cellular systems. Its utility in chemical biology makes it a valuable tool for investigating protein interaction dynamics and therapeutic development.
Product Information
Catalog NumA40918
FormulaC42H63N3O11
Molecular Weight785.96
CAS Number2765059-01-4
SMILESNCCCOCCOCCOCCCNC(COC1=CC=CC([C@H](OC([C@@H]2CCCCN2C(C(C(C)(C)CC)=O)=O)=O)CCC3=CC(OC)=C(OC)C=C3)=C1)=O
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