Flibanserin-d4-1 is a deuterated form of Flibanserin, a full agonist of the serotonin 5-HT1A receptor (Ki=1 nM) and an antagonist of the 5-HT2A receptor (Ki=49 nM). Additionally, Flibanserin demonstrates binding affinity for dopamine D4 receptors (4-24 nM) while exhibiting minimal interactions with various other neurotransmitter receptors and ion channels. This compound is primarily utilized in research applications focused on hypoactive sexual desire disorder (HSDD) and the underlying mechanisms of serotonergic and dopaminergic signaling.
Flibanserin-d4-1 is a deuterated form of Flibanserin, a full agonist of the serotonin 5-HT1A receptor (Ki=1 nM) and an antagonist of the 5-HT2A receptor (Ki=49 nM). Additionally, Flibanserin demonstrates binding affinity for dopamine D4 receptors (4-24 nM) while exhibiting minimal interactions with various other neurotransmitter receptors and ion channels. This compound is primarily utilized in research applications focused on hypoactive sexual desire disorder (HSDD) and the underlying mechanisms of serotonergic and dopaminergic signaling.
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