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FLT3/CDKs ligand-1

Ligand for Target Protein in PROTAC

FLT3/CDKs ligand-1 is a potent ligand designed for the targeted degradation of cyclin-dependent kinase (CDK) and FMS-like tyrosine kinase 3 (FLT3). This compound effectively inhibits FLT3/CDK-related proliferation and survival of leukemia cells, making it a valuable tool for cancer research. FLT3/CDKs ligand-1 facilitates the synthesis of PROTAC FLT3/CDKs degrader-1, enabling innovative approaches in targeted protein degradation studies.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Ligand / Binder
CAS Number	2452019-67-7
Applications	Ligand for Target Protein in PROTAC
Formula	C₂₆H₃₁N₉O₃
Molecular Weight	517.58
SMILES	O=C(C1=NNC=C1NC2=C3C(NC=C3)=NC=N2)NC4=CC=C(CN5CCN(C(OC(C)(C)C)=O)CC5)C=C4

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.