Fig. 1 · Structure
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FLT3 ligand-2
Ligand for Target Protein for PROTAC
FLT3 ligand-2 is a potent ligand for the FLT3 target protein, facilitating the development of PROTACs (proteolysis-targeting chimeras). This compound is utilized to synthesize PROTAC FLT-3 degrader 1, which promotes the selective degradation of FLT3 in targeted therapies. Its application is crucial in research focused on eradicating FLT3-driven malignancies, contributing to advancements in cancer treatment strategies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Ligand / Binder |
| CAS Number | 950769-51-4 |
| Applications | Ligand for Target Protein for PROTAC |
| Formula | C23H21N5O3S |
| Molecular Weight | 447.51 |
| SMILES | OC1=CC2=C(N3C(S2)=NC(C4=CC=C(NC(NC5=NOC(C(C)(C)C)=C5)=O)C=C4)=C3)C=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.