Fig. 1 · Structure
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Flucofuron
Antiinfection Agent
Flucofuron is an anti-infection agent that effectively targets trophozoites of Naegleria fowleri, demonstrating IC50 values of 2.58 μM and 2.47 μM against strains ATCC 30808 and ATCC 30215, respectively. Notably, it also exhibits activity against the resistant cyst stage, with an IC50 of 0.88 μM. Flucofuron induces apoptosis in cells and is applicable in research related to infections and inflammatory conditions, including Primary amoebic meningoencephalitis (PAM).
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 370-50-3 |
| Applications | Antiinfection Agent |
| Formula | C15H8Cl2F6N2O |
| Molecular Weight | 417.13 |
| SMILES | O=C(NC1=CC=C(Cl)C(C(F)(F)F)=C1)NC2=CC=C(Cl)C(C(F)(F)F)=C2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.