Fig. 1 · Structure
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Fludarabine-Cl
ADAR1 Inhibitor
Fludarabine-Cl is a selective inhibitor of RNA adenosine deaminase 1 (ADAR1), exhibiting an IC50 value of 0.87 μM. This compound plays a critical role in research related to cancer and tumor-related diseases by modulating the activity of ADAR1, which is involved in RNA editing processes. Fludarabine-Cl can be utilized in various experimental contexts to explore the biological implications of ADAR1 inhibition.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2734853-80-4 |
| Applications | ADAR1 Inhibitor |
| Formula | C10H11ClFN5O3 |
| Molecular Weight | 303.68 |
| SMILES | NC1=C2C(N([C@]3([H])O[C@@H]([C@H]([C@H]3O)O)CCl)C=N2)=NC(F)=N1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.