Fig. 1 · Structure
Documents & Downloads
Fluorizoline
Antitumor Agent
Fluorizoline is an antitumor agent that selectively and directly binds to prohibitin 1 (PHB1) and prohibitin 2 (PHB2), promoting apoptosis in cancer cells. It effectively reduces cell viability in chronic lymphocytic leukemia (CLL) by upregulating pro-apoptotic factors NOXA and BIM. Notably, Fluorizoline exerts its antitumor effects independent of the p53 pathway, making it a valuable tool for research in cancer biology and therapeutic development.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1362243-70-6 |
| Applications | Antitumor Agent |
| Formula | C15H8Cl2F3NS |
| Molecular Weight | 362.20 |
| SMILES | FC1(C(F)(N=C(S1)C2=CC=C(C=C2)Cl)F)C3=CC=C(C=C3)Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.