Fluticasone is a synthetic corticosteroid that acts as an agonist of the Smoothened (Smo) receptor, with an IC50 value of 99 nM. This compound activates Hedgehog signaling pathways, promoting the proliferation of primary neuronal stem or precursor cells. Fluticasone is utilized in respiratory research and can provide insights into mechanisms related to cell growth and differentiation within the context of Hedgehog signaling.
Fluticasone is a synthetic corticosteroid that acts as an agonist of the Smoothened (Smo) receptor, with an IC50 value of 99 nM. This compound activates Hedgehog signaling pathways, promoting the proliferation of primary neuronal stem or precursor cells. Fluticasone is utilized in respiratory research and can provide insights into mechanisms related to cell growth and differentiation within the context of Hedgehog signaling.
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