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Fluvastatin sodium monohydrate

HMGCR Inhibitor

Fluvastatin sodium monohydrate is a competitive inhibitor of HMG-CoA reductase (HMGCR) with an IC50 of 8 nM. This compound showcases significant protective effects on vascular smooth muscle cells by mitigating oxidative stress through the Nrf2-dependent antioxidant pathway. It is primarily utilized in research focused on lipid metabolism, cardiovascular diseases, and related mechanisms of oxidative stress response.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	201541-53-9
Applications	HMGCR Inhibitor
Formula	C₂₄H₂₇FNNaO₅
Molecular Weight	451.46
Synonyms	XU 62-320 monohydrate
SMILES	O=C(O[Na])C[C@@H](O)C[C@@H](O)/C=C/C1=C(C2=CC=C(C=C2)F)C3=CC=CC=C3N1C(C)C.O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.