Fig. 1 · Structure
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FMF-04-159-R
CDK14/CDK16 Inhibitor
FMF-04-159-R is an inhibitor of cyclin-dependent kinases CDK14 and CDK16, exhibiting IC50 values of 5.9 nM and 139.1 nM, respectively. This compound is primarily utilized in research to explore the roles of CDK14 and CDK16 in cell cycle regulation and transcriptional control. Its selective inhibition may provide insights into therapeutic strategies for diseases linked to dysregulated kinase activity.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2741262-15-5 |
| Applications | CDK14/CDK16 Inhibitor |
| Formula | C28H32Cl3N7O5S |
| Molecular Weight | 685.02 |
| SMILES | O=C(C1=NNC=C1NC(C2=C(Cl)C=C(Cl)C=C2Cl)=O)NC3CCN(S(=O)(C4=CC(NC(CCCN(C)C)=O)=CC=C4)=O)CC3 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.