Fig. 1 · Structure
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Fmoc-Aeg(N3)-OH
Click Chemistry Reagent
Fmoc-Aeg(N3)-OH is a click chemistry reagent featuring an azide functional group, enabling efficient copper-catalyzed azide-alkyne cycloaddition (CuAAc) and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions. This compound facilitates the synthesis of peptoid structures through alkylation of the nitrogen in amide bonds, leading to conformational restraints and modifications in pharmacological profiles. It is particularly valuable for designing macrocycles, stabilizing backbones via intermolecular ring closure, and constructing customized peptide nucleic acids (PNAs). Fmoc-Aeg(N3)-OH serves as a versatile building block for the advancement of selective cytotoxic agents and receptor-specific agonists.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1935981-35-3 |
| Applications | Click Chemistry Reagent |
| Formula | C19H18N4O4 |
| Molecular Weight | 366.37 |
| SMILES | [N-]=[N+]=NCCN(CC(O)=O)C(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.