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Fmoc-D-homoArg(Et)2-OH hydrochloride

Arg Derivative

Fmoc-D-homoArg(Et)2-OH hydrochloride is a Fmoc-protected derivative of D-Homoarginine, designed to confer resistance to proteolysis by trypsin in peptides and proteins. This compound serves as a valuable tool for the synthesis of antibody-drug conjugates (ADCs), functioning as a cleavable linker that enhances the stability and efficacy of the conjugates. Its unique properties make it a suitable candidate for applications in drug development and peptide synthesis.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	2098497-24-4
Applications	Arg Derivative
Formula	C₂₆H₃₅ClN₄O₄
Molecular Weight	503.03

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.