Fig. 1 · Structure
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Fmoc-Gly-Gly-allyl propionate
Linker
Fmoc-Gly-Gly-allyl propionate is a cleavable linker designed for the synthesis of Antibody-Drug Conjugates (ADCs). This compound facilitates the selective release of therapeutic agents in targeted applications, enhancing the efficacy of ADCs in cancer treatment. Its ability to provide stable linkage while allowing for subsequent cleavage makes it a valuable tool in chemical biology and drug development research.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 2766214-15-5 |
| Applications | Linker |
| Formula | C25H26N2O7 |
| Molecular Weight | 466.48 |
| SMILES | C=CCOC(CC[C@@H](C(O)=O)NC(CNC(OCC1C2=CC=CC=C2C3=CC=CC=C31)=O)=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.