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Fmoc-L-Asn(EDA-N3)-OH

Azide Compound

Fmoc-L-Asn(EDA-N3)-OH is an azide-containing click chemistry reagent designed for selective biochemical modifications. Its unique structure allows for efficient copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-functionalized molecules, as well as ring strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN groups. This reagent has been utilized in studies involving the modification of alpha-amanitin, a potent allosteric inhibitor of RNA polymerase II, facilitating advancements in understanding its biological activity and potential applications in molecular biology and drug design.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	2616562-74-2
Applications	Azide Compound
Formula	C₂₁H₂₁N₅O₅
Molecular Weight	423.42
SMILES	[N-]=[N+]=NCCNC(C[C@@H](C(O)=O)NC(OCC1C2=CC=CC=C2C3=CC=CC=C31)=O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.