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Fmoc-L-Lys(Pentynoyl-DIM)-OH

Click Chemistry Reagent

Fmoc-L-Lys(Pentynoyl-DIM)-OH is a click chemistry reagent known for its azide functionality. This compound serves as a valuable building block in solid-phase peptide synthesis (SPPS), facilitating the purification of highly insoluble peptides through the "helping hand" strategy. The incorporation of solubilizing residues via click chemistry enhances peptide solubility, with the tags readily removable using 1M hydrazine or hydroxylamine. Additionally, it is capable of undergoing copper-catalyzed azide-alkyne cycloaddition (CuAAc) and ring strain-promoted alkyne-azide cycloaddition (SPAAC) with alkyne-containing entities, making it versatile for various biochemical applications.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	2408993-33-7
Applications	Click Chemistry Reagent
Formula	C₃₄H₃₈N₂O₆
Molecular Weight	570.68
SMILES	C#CCC/C(NCCCC[C@@H](C(O)=O)NC(OCC1C2=CC=CC=C2C3=CC=CC=C31)=O)=C4C(CC(C)(CC/4=O)C)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.