Fig. 1 · Structure
Documents & Downloads
Fmoc-leucine-d10
Stable Isotope
Fmoc-leucine-d10 is a deuterium-labeled derivative of Fmoc-leucine, targeting the peroxisome proliferator-activated receptor gamma (PPARγ). This compound acts as a selective modulator, exhibiting similar maximal efficacy to rosiglitazone but with lower potency. Fmoc-leucine-d10 has been shown to enhance insulin sensitivity in various models, including normal, diet-induced glucose-intolerant, and diabetic db/db mice, while demonstrating reduced adipogenic activity. Its unique isotopic labeling enables advanced studies in metabolic research.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1190594-22-9 |
| Applications | Stable Isotope |
| Formula | C21H13D10NO4 |
| Molecular Weight | 363.47 |
| SMILES | [2H]C([2H])([2H])C(C([2H])([2H])[2H])([2H])C([2H])([2H])[C@](C(O)=O)([2H])NC(OCC1C2=CC=CC=C2C3=CC=CC=C31)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.