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Fmoc-PNA-thioU(PMB)-OH

PNA Monomer

Fmoc-PNA-thioU(PMB)-OH is a nucleobase-modified peptide nucleic acid (PNA) monomer featuring a thiouracil base that is protected with a p-methoxybenzyl (PMB) group on an Fmoc-protected backbone. This compound is utilized in solid-phase synthesis to incorporate modified PNA bases into oligonucleotides, facilitating the study of their binding properties and interactions. It is particularly valuable for research applications focused on understanding nucleic acid behavior, molecular recognition, and the development of nucleic acid-based therapeutics.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	2245800-85-3
Applications	PNA Monomer
Formula	C₃₃H₃₂N₄O₇S
Molecular Weight	628.69

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.