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Fmoc-Val-Lys(Boc)-PAB-Exatecan

Anticancer Agent

Fmoc-Val-Lys(Boc)-PAB-Exatecan is a drug-linker conjugate specifically designed for antibody-drug conjugate (ADC) applications. This compound features the cytotoxic agent Exatecan linked through a PAB-Val-Lys-Boc moiety, enhancing its target specificity and therapeutic efficacy. Fmoc-Val-Lys(Boc)-PAB-Exatecan is ideal for the synthesis of ADCs aimed at delivering potent anti-cancer activity while minimizing systemic toxicity, thus contributing to advancements in targeted cancer therapies.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	2901788-26-7
Applications	Anticancer Agent
Formula	C₆₃H₆₈FN₇O₁₂
Molecular Weight	1134.25
SMILES	O=C(OCC1C2=CC=CC=C2C3=CC=CC=C31)N[C@@H](C(C)C)C(N[C@@H](CCCCNC(OC(C)(C)C)=O)C(NC(C=C4)=CC=C4COC(N[C@@H]5C6=C7C(C(N8C7)=CC([C@](O)(C(OC9)=O)CC)=C9C8=O)=NC%10=CC(F)=C(C)C(CC5)=C%106)=O)=O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.