Biological Activity
FN-1501 is a potent inhibitor of FLT3 and CDK, with IC50s of 2.47, 0.85, 1.96, and 0.28 nM for CDK2/cyclin A, CDK4/cyclin D1, CDK6/cyclin D1 and FLT3, respectively. FN-1501 has anticancer activity.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 23.18 mL | 115.88 mL | 231.76 mL |
0.5 mM | 4.64 mL | 23.18 mL | 46.35 mL |
1 mM | 2.32 mL | 11.59 mL | 23.18 mL |
5 mM | 0.46 mL | 2.32 mL | 4.64 mL |
*The above data is based on the productmolecular weight 431.49. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Catalog Num | A13559 |
---|---|
Actions | Inhibitor |
M. Wt | 431.49 |
Formula | C22H25N9O |
Solubility | DMSO |
Purity | >98% |
Storage | at -20°C 3 years Powder |
CAS No. | 1429515-59-2 |
Synonyms | FN1501, FN 1501 |
SMILES | O=C(C1=NNC=C1NC2=NC=NC3=C2C=CN3)NC4=CC=C(CN5CCN(C)CC5)C=C4 |
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