Fig. 1 · Structure
Documents & Downloads
Folinic acid calcium hydrate
Biological Folic Acid
Folinic acid calcium hydrate, a biological form of folic acid, primarily serves as a rescue agent to mitigate the toxicity associated with Methotrexate treatment. It is utilized in various therapeutic protocols to counteract the effects of folate antagonists, ensuring a safer treatment regimen. Folinic acid is crucial in oncological and hematological research applications, where it plays a key role in supporting cellular processes influenced by folate metabolism.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 1097832-14-8 |
| Applications | Biological Folic Acid |
| Formula | C20H25CaN7O8 |
| Molecular Weight | 531.53 |
| Synonyms | Leucovorin calcium hydrate |
| SMILES | O=C(O)CC[C@@H](C(O)=O)NC(C1=CC=C(NCC2N(C=O)C3=C(N=C(N)NC3=O)NC2)C=C1)=O.[Ca].O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.