Fig. 1 · Structure
Documents & Downloads
Folinic acid disodium
Biological Folic Acid
Folinic acid disodium is a biologically active form of folic acid (vitamin B9) that acts as a leucovorin rescue agent. It is primarily used to mitigate the toxic effects of methotrexate in various chemotherapeutic regimens. Additionally, folinic acid disodium enhances the efficacy of 5-fluorouracil in adjuvant chemotherapy for colon carcinoma, making it a valuable reagent in cancer research and treatment applications.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 163254-40-8 |
| Applications | Biological Folic Acid |
| Formula | C20H21N7Na2O7 |
| Molecular Weight | 517.40 |
| Synonyms | Leucovorin disodium |
| SMILES | O=C(O[Na])CC[C@@H](C(O[Na])=O)NC(C1=CC=C(NCC2N(C=O)C3=C(NC(N)=NC3=O)NC2)C=C1)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.